AI Engineering/Phase 14/Lesson 18

Agno and Mastra: Production Runtimes

Agno (Python) and Mastra (TypeScript) are the 2026 production-runtime pairing. Agno aims at microsecond agent instantiation and stateless FastAPI backends. Mastra ships agents, tools, workflows, unified model routing, and composite storage on the Vercel AI SDK substrate.

Learn 45 min Python, TypeScript

Prerequisites: Phase 14 · 01 (Agent Loop), Phase 14 · 13 (LangGraph)

#Learning Objectives

Identify Agno's performance targets and when they matter.
Name Mastra's three primitives — Agents, Tools, Workflows — and the supported server adapters.
Explain why a stateless session-scoped FastAPI backend is the recommended Agno production path.
Pick Agno vs Mastra for a given stack (Python-first vs TypeScript-first).

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The text and code of this lesson are based on AI Engineering from Scratch by Rohit Ghumare, MIT licensed.